Episode 56: Cannabis and Heart Health — Unpacking the Evidence Behind Cardiovascular Risk

This week on The Tox Lab, we are examining the growing evidence around cannabis and cardiovascular risk.

We start with a recent systematic review and meta-analysis that explores whether cannabis use is linked to higher rates of cardiovascular disease. We break down the strength of the data and discuss what the current evidence can and cannot tell us.

We then move onto research investigating how THC and its metabolites affect cardiac myocyte structure and function. These findings offer a possible mechanistic explanation for cardiac dysregulation and may help connect population-level associations with cellular effects.

Join us as we unpack the toxicology, the uncertainties, and what this emerging research means for clinicians, researchers, and anyone interested in the evolving science of cannabis and heart health.

Hope you enjoy!

Links to the papers we discussed:

https://heart.bmj.com/content/111/22/1047.long

https://www.ahajournals.org/doi/10.1161/JAHA.123.030178

https://pmc.ncbi.nlm.nih.gov/articles/PMC8835806/pdf/ijms-23-01401.pdf

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