Episode 29: Delta-8 THC vs Delta-9 THC – How One Double Bond Alters Clinical Effects

In this week’s episode, we explore the growing world of delta-8 THC—how it compares to delta-9 THC, what recent research reveals about its effects when consumed orally, and what those differences might mean for users. We also discuss a pediatric case involving the accidental ingestion of delta-8 THC gummies, highlighting the clinical presentation, management, and the testing challenges that can arise.

Hope you enjoy!

Links to papers we discussed:

https://doi.org/10.1016/j.drugalcdep.2025.112676

https://pmc.ncbi.nlm.nih.gov/articles/PMC8594112/

https://www.sciencedirect.com/science/article/abs/pii/S0376871625001371?via%3Dihub

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